Hui-Chen Cheng

Ophthalmology

Section Chief

Neuro-Ophthalmology and strabismus, Glaucoma, General ophthalmology

MD, National Yang-Ming University, Taipei, Taiwan
Ph.D., Program in Molecular Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan

Residency, Department of Family Medicine, Taipei Veterans General Hospital, Taoyuan branch, Taoyuan, Taiwan

Residency, Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan

Fellowship (Neuro-ophthalmology & Strabismus, Glaucoma), Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan 

Member, Ophthalmological Society of Taiwan

Attending physician, Section of Neuro-ophthalmology & Strabismus, Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan

• National board of Ophthalmology
• Certificate of 2013 International Society for Clinical Electrophysiology of Vision (ISCEV) training course
• Taiwan medical licensing examination
• Advanced cardiac life support provider

1. Cheng HC, Lee SM, Lee FL, Liu JH, Kuan CH, Lin PK. Short-term external buckling with pneumatic retinopexy for retinal detachment with inferior retinal breaks. Am J Ophthalmol. 2013;155(4):750-756, 756 e751.

2. Cheng HC, Lin PK. Reply. Am J Ophthalmol. 2013;156(3):625-626.

3. Cheng HC, Yen MY, Wang AG. Foville’s syndrome with ipsilateral internuclear ophthalmoplegia due to spontaneous pontine hemorrhage. Taiwan Journal of Ophthalmology. 2013;3:75-77.

4. Cheng HC, Liu JH, Lee SM, Lin PK. Hyperhomocysteinemia in patients with polypoidal choroidal vasculopathy: a case control study. PLoS One. 2014;9(10):e110818.

5. Cheng HC, Tsai RK, Woung LC, Yen MY, Wang AG. Proceedings of the Neuro-ophthalmology Symposium in the 54th Annual Meeting of the Ophthalmological Society of Taiwan, November 30, 2013, Taipei, Taiwan. Neuro-Ophthalmology. 2014;38(3):167-169.

6. Cheng HC, Guo CY, Chen MJ, Ko YC, Huang N, Liu CJ. Patient-reported vision-related quality of life differences between superior and inferior hemifield visual field defects in primary open-angle glaucoma. JAMA Ophthalmol. 2015;133(3):269-275.

7. Cheng HC, Lee SM, Hsieh YT, Lin PK. Efficacy of intravitreal injection of anti-vascular endothelial growth factor agents for stage 4 retinopathy of prematurity. Retina. 2015;35(4):660-666.

8. Cheng HC, Yeh HJ, Huang N, Chou YJ, Yen MY, Wang AG. Amiodarone-Associated Optic Neuropathy: A Nationwide Study. Ophthalmology. 2015;122(12):2553-2559.

9. Cheng HC, Yen MY, Wang AG. Neuroimaging and clinical features of patients with optic nerve hypoplasia in Taiwan. Taiwan Journal of Ophthalmology. 2015;5(1):15-18.

10. Cheng HC, Guo CY, Chen YJ, et al. Patient-Reported Vision-Related Quality-of-Life Differences between Primary Angle-Closure Glaucoma and Primary Open-Angle Glaucoma. PLoS One. 2016;11(9):e0163123.

11. Cheng HC, Huang TL, Lin KJ, et al. Summary of the Neuro-ophthalmology Symposium in the 31st Asia-Pacific Academy of Ophthalmology Congress (APAO 2016). Neuro-Ophthalmology. 2016;40(5):251-253.

12. Cheng HC, Pan RH, Yeh HJ, et al. Ambient Air Pollution and the Risk of Central Retinal Artery Occlusion. Ophthalmology. 2016;123(12):2603-2609.

13. Cheng HC, Yeh HJ, Huang N, Wang AG. Reply. Ophthalmology. 2016;123(10):e59-60.

14. Kuo YS, Liu CJ, Cheng HC, Chen MJ, Chen WT, Ko YC. Impact of socioeconomic status on vision-related quality of life in primary open-angle glaucoma. Eye (Lond). 2017;31(10):1480-1487.

15. Wang AG, Cheng HC. Amiodarone-Associated Optic Neuropathy: Clinical Review. Neuroophthalmology. 2017;41(2):55-58.

16. Lee CW, Cheng HC, Chang FC, Wang AG. Optical Coherence Tomography Angiography Evaluation of Retinal Microvasculature Before and After Carotid Angioplasty and Stenting. Sci Rep. 2019;9(1):14755.

17. Lo KJ, Wang AG, Cheng HC*. Retinal Vasculature Changes after Bypass Surgery for Moyamoya Disease. Ophthalmology. 2021;128(1):120. (*corresponding author)

18. Lo KJ, Yang JH, Cheng HC, Chang HY, Lin TC. Recovery of visual field defects following vitrectomy for proliferative diabetic retinopathy: A case report. Medicine (Baltimore). 2021;100(48):e27793.

19. Cheng HC, Chi SC, Liang CY, Yu JY, Wang AG. Candidate Modifier Genes for the Penetrance of Leber's Hereditary Optic Neuropathy. Int J Mol Sci. 2022;23(19).

20. Chi SC, Cheng HC#, Wang AG. Leber Hereditary Optic Neuropathy: Molecular Pathophysiology and Updates on Gene Therapy. Biomedicines. 2022;10(8). (#co-first author)

21. Chiou YR, Cheng HC, Wang AG. Astrocytic hamartoma in a patient heterozygous for RIM1 mutation associated-retinal dystrophy. Ophthalmic Genet. 2022;43(3):409-412.

22. Hung WC, Cheng HC, Wang AG. Melanoma-associated retinopathy with anti-TRPM1 autoantibodies showing concomitant Off-bipolar cell dysfunction. Doc Ophthalmol. 2022;145(3):263-270.

23. Wu RY, Sung WH, Cheng HC, Yeh HJ. Investigating the rate of skeletal muscle atrophy in men and women in the intensive care unit: a prospective observational study. Sci Rep. 2022;12(1):16629.

24. Yeh HJ, Chen TA, Cheng HC, Chou YJ, Huang N. Long-Term Rehabilitation Utilization Pattern Among Stroke Patients Under the National Health Insurance Program. Am J Phys Med Rehabil. 2022;101(2):129-134.

25. Yeh TC, Cheng HC#, Li HY, et al. Ophthalmic characteristics and retinal vasculature changes in Williams syndrome, and its association with systemic diseases. Eye (Lond). 2023;37(11):2265-2271. (#co-first author)

26. Yeh TC, Niu DM, Cheng HC, et al. Novel mutation of IFT140 in an infant with Mainzer-Saldino syndrome presenting with retinal dystrophy. Mol Genet Metab Rep. 2022;33:100937.

27. Carelli V, Newman NJ, Yu-Wai-Man P, et al. Indirect Comparison of Lenadogene Nolparvovec Gene Therapy Versus Natural History in Patients with Leber Hereditary Optic Neuropathy Carrying the m.11778G>A MT-ND4 Mutation. Ophthalmol Ther. 2023;12(1):401-429. [LHON study group]

28. Chen IH, Chang HH, Chiu HI, Cheng HC, Wang AG. Autosomal Recessive Leber Hereditary Optic Neuropathy in a Patient With a Novel NDUFAF2 Compound Heterozygous Mutation. J Neuroophthalmol. 2023.

29. Chiu HI, Chiu HC, Wu CC, Cheng HC, Wang AG. Acute Myeloid Leukemia With Extramedullary Myeloid Sarcoma Presenting as Optic Neuropathy. J Neuroophthalmol. 2023.

30. Liou RH, Chen SW, Cheng HC, et al. The efficient induction of human retinal ganglion-like cells provides a platform for studying optic neuropathies. Cell Mol Life Sci. 2023;80(8):239.

31. Newman NJ, Yu-Wai-Man P, Subramanian PS, et al. Randomized trial of bilateral gene therapy injection for m.11778G>A MT-ND4 Leber optic neuropathy. Brain. 2023;146(4):1328-1341. [LHON study group]

32. Yeh, H. J.; Cheng, H. C.; Huang, S. C.; Cheng, S. P., Does positive feedback or appraisal about medical providers increase patients' trust and lead to better treatment outcomes? A double-blind randomized control trial. J Phys Ther Sci 2023, 35, (12), 802-809.

33. Su, Y. W.; Wang, A. G.; Cheng, H. C.*, Retinal Vasculature Changes Herald the Presence of Carotid-Cavernous Fistula. Ophthalmology 2023. (*corresponding author)

34. Hung, W. C.; Chen, H. H.; Yeh, H. J.; Wang, A. G.; Cheng, H. C.*, Ocular Electrophysiologic Studies in a Patient With Anti-NMDA Receptor Encephalitis and Visual Dysfunction: A Case Report. J Neuroophthalmol 2024. (*corresponding author)

35. Chiu HI, Cheng HC, Wu CC, et al. Exome sequencing and genome-wide association analyses unveils the genetic predisposition in hydroxychloroquine retinopathy. Eye (Lond). 2024;38(10):1926-1932.